Innovations in Toxin Removal
There are several bacterial-derived bioactive substances that cause enteric diseases, triggering immune and proinflammatory reactions in animals. Among the main infectious agents, we can point out E. coli and Clostridium sp.
• Exotoxins are proteins actively secreted by Gram-positive and Gram -negative bacteria during their growth.
• Endotoxins are lipopolysaccharides (LPS), which are constituents of the outer membrane of Gram-negative bacteria, being released during bacterial growth or cellular lysis.
Aerobic fungi, especially from the genera Fusarium sp. and Aspergillus sp., produce metabolic toxins, which are present in grains, byproducts and conserved forages (hay and silage) offered to livestock. Their main effects in animals are the reduced feed intake, performance, immunity and fertility, as well as higher incidence of reproductive disorders.
“Around 400 different mycotoxins are known, of which the most harmful are Aflatoxin, Fumonisin, Zearalenone, T2 toxin, and DON, which can act individually or synergistically leveraging its negative effects on the animal.”
Mixing adsorbents in feed is the most suitable form of prevention, because they chemically bind to toxins in the gastrointestinal tract, decreasing their bioavailability and toxicity.
The choice of adsorbent should ideally take into account:
• Ability to adsorb high concentrations of toxins;
• Selectivity of the adsorbent;
• Inclusion rate;
And all these results must be confirmed by laboratory reports (IN13).